A high performance computing infrastructure for medical data
Scope
The scope of PRECIOUS (Research Infrastructure for big medical data analytics towards precision medicine) (MIS 5047133) that is implemented under the Action “Reinforcement of the Research and Innovation Infrastructure”, funded by the Operational Programme "Competitiveness, Entrepreneurship and Innovation" (NSRF 2014-2020) and co-financed by Greece and the European Union (European Regional Development Fund) is to implement an innovative cloud platform which will provide health services, on demand, for the interconnection of disperse medical centers with the aim of sharing, harmonizing and subsequently extracting information from different types of big medical data, including histopathological, laboratory, clinical, omics, biosignals, etc.
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Encrypted connection services for federated data sharing and storage -
Tools for data quality control and data harmonization
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Federated analysis of large heterogeneous medical data through AI technologies towards the development of AI models for precision medicine
Objectives
The implementation of PRECIOUS requires the interdisciplinary collaboration of data scientists, software engineers, medical doctors, bioinformaticians, biologists, and economists. The primary objectives of PRECIOUS include the following:
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Interconnection of heterogeneous medical and clinical centers -
Medical data quality enhancement
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Construction of semantic data models (ontologies) for various clinical domains
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Harmonization of heterogeneous medical data sources
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Detection of new biomarkers/validation of existing one
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Development of robust risk stratification models and accurate disease prediction models
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Suggestion of targeted therapeutic treatments
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Distillation of novel associations between phenotypes
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Visualization of high-dimensional data structures
Increase performace with PRECIOUS hosting
PRECIOUS architecture is based on Hyper-converged infrastructure (HCI)
